A structured tree outflow condition provides a physiologically adequate and computationally feasible boundary condition for modeling blood flow in systemic arteries.
Facilitates dynamic arterial flow simulations in research; leaves open clinical translation pending validation.
A central problem in modeling blood flow and pressure in the larger systemic arteries is determining a physiologically based boundary condition so that the arterial tree can be truncated after a few generations. We have used a structured tree attached to the terminal branches of the truncated arterial tree in which the root impedance is estimated using a semianalytical approach based on a linearization of the viscous axisymmetric Navier-Stokes equations. This provides a dynamic boundary condition that maintains the phase lag between blood flow and pressure as well as the high-frequency oscillations present in the impedance spectra. Furthermore, it accommodates the wave propagation effects for the entire systemic arterial tree. The result is a model that is physiologically adequate as well as computationally feasible. For validation, we have compared the structured tree model with a pure resistance and a windkessel model as well as with measured data.
No takes yet. Share an insight, caveat, or question.
Mette S. Olufsen (1999) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: