Key result
Low admission GNRI is linked to a ~6-fold increase in 1-year heart failure readmissions.
Why the study?
Malnutrition is linked to hospital readmissions in acute decompensated heart failure, but the optimal objective nutritional index to predict prognosis in older adults remained to be determined.
Does a low Geriatric Nutritional Risk Index (GNRI) predict unplanned hospitalization for worsening heart failure in older adults admitted with acute decompensated heart failure?
Cohort (n=167)
No
Does a low Geriatric Nutritional Risk Index (GNRI) predict unplanned hospitalization for worsening heart failure in older adults admitted with acute decompensated heart failure?
The Geriatric Nutritional Risk Index (GNRI) is a strong predictor of 1-year readmission for worsening heart failure in older adults with acute decompensated heart failure, irrespective of ejection fraction.
Answers are grounded in this paper and cite their sources.
GNRI screening may stratify readmission risk in older ADHF patients; extends malnutrition data but leaves open whether intervention reduces events.
Objectives: Malnutrition is associated with an increased risk of hospital readmission for heart failure in patients with acute decompensated heart failure (ADHF). Therefore, evaluation of the nutritional status in patients with ADHF may be important. The geriatric nutritional risk index (GNRI), the controlling nutritional status (CONUT) score, and the prognostic nutritional index (PNI) are widely used objective indexes for evaluation of the nutritional status. The present study was performed to determine the best nutritional index for predicting the prognosis in older adults with ADHF. Methods: We retrospectively studied 167 older adults (>65 years of age) who were admitted with ADHF from January 2012 to December 2015 and discharged alive. The objective nutritional status was evaluated using the GNRI, CONUT score, and PNI at admission. The endpoint of this study was unplanned hospitalization for worsening heart failure (WHF) within 1 year after discharge. Results: <0.0001; hazard ratio, 6.1; 95% confidence interval, 3.5-10.5). Conclusion: Among the objective nutritional indexes, the GNRI is the best predictor of readmission for WHF within 1 year after discharge in older adults with ADHF.
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Sato et al. (2023) conducted a cohort in Acute decompensated heart failure (n=167). Low Geriatric Nutritional Risk Index (GNRI <90) vs. High Geriatric Nutritional Risk Index (GNRI ≥90) was evaluated on Unplanned hospitalization for worsening heart failure within 1 year after discharge (HR 6.1, 95% CI 3.5-10.5, p=<0.0001). A low Geriatric Nutritional Risk Index (<90) at admission was associated with a significantly increased risk of 1-year unplanned readmission for worsening heart failure (HR 6.1) in older adults.
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