March 30, 2010European Journal of Heart FailureOpen Access

Endothelial Dysfunction, Measured by Reactive Hyperaemia Using Strain-Gauge Plethysmography, is an Independent Predictor of Adverse Outcome in Heart Failure

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Why the study?

Does endothelial dysfunction, measured by reactive hyperaemia, predict adverse outcomes in patients with congestive heart failure?

Population

242 patients with congestive heart failure (CHF)

Design

Cohort

Follow-up

5 years

Authors

JBJosé R. BerrazuetaPontificia Universidad Católica del Ecuador ARArmando RuizMarqués de Valdecilla University Hospital MGMaría Teresa García‐UnzuetaUniversidad de Cantabria

Discussion

Member takes

Implication

Endothelial dysfunction assessment may refine HF prognostication; hypothesis-generating and requires prospective validation before clinical adoption.

Structured PICO

Does endothelial dysfunction, measured by reactive hyperaemia, predict adverse outcomes in patients with congestive heart failure?

Population

242 patients with congestive heart failure (CHF)

Intervention

Assessment of endothelial function by forearm reactive hyperaemia measured with intermittent venous occlusion plethysmography using a mercury strain gauge

Outcome

Composite of 'total events' (death, heart attack, angina, stroke, NYHA class IV, or hospitalization due to heart failure) and 'death'composite

Endothelial dysfunction, measured by post-hyperaemia forearm blood flow, is an independent predictor of major adverse events in patients with congestive heart failure.

Cite This Study

Berrazueta et al. (2010) studied this question.

synapsesocial.com/papers/6a1a382a31dddbe2d1afa640 https://doi.org/10.1093/eurjhf/hfq036

Topics

Heart failure HFrEF treatment HFpEF management

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Bookmark

Implication

Endothelial dysfunction assessment may refine HF prognostication; hypothesis-generating and requires prospective validation before clinical adoption.

Endothelial Dysfunction, Measured by Reactive Hyperaemia Using Strain-Gauge Plethysmography, is an Independent Predictor of Adverse Outcome in Heart Failure

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Endothelial Dysfunction, Measured by Reactive Hyperaemia Using Strain-Gauge Plethysmography, is an Independent Predictor of Adverse Outcome in Heart Failure

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider