August 1, 1990Pacing and Clinical Electrophysiology

Is Accurate Rate Response Programming Necessary?

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Why the study?

Does accurate rate response programming improve exercise capacity and general well-being compared to inaccurate programming in patients with pacemakers?

Structured PICO

Does accurate rate response programming improve exercise capacity and general well-being compared to inaccurate programming in patients with pacemakers?

Population

20 patients (10 with combined AV block and sinus node incompetence implanted with activity sensing DDDR units, 10 with complete heart block implanted with Sensolog activity sensing VVIR units)

Intervention

Appropriate rate response programming (VVIR, DDDR according to manufacturer's instructions) and over-responsive programming (VVIR+, DDDR+)

Comparator

Absent rate response (VVI) or hyporesponsive programming (DDD)

Outcome

Subjective assessment by visual analog scales and specific activity questionnaires, and objective assessment by graded treadmill testing and performance of standardized daily activitiespatient reported

Appropriate rate response programming is critical in pacemakers, as overprogramming reduces general well-being despite objective improvements in exercise capacity.

Discussion

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Implication

Accurate rate-response programming maximizes well-being over exercise gains from over-responsive modes; confirms individualized settings as essential in pacemaker care and trials.

Cite This Study

Sulke et al. (1990) studied this question.

synapsesocial.com/papers/6a1a6ae686df338625855455 https://doi.org/10.1111/j.1540-8159.1990.tb02150.x

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Implication

Accurate rate-response programming maximizes well-being over exercise gains from over-responsive modes; confirms individualized settings as essential in pacemaker care and trials.