Why the study?
Does renal sympathetic activity differ between spontaneously hypertensive rats and normotensive controls?
Does renal sympathetic activity differ between spontaneously hypertensive rats and normotensive controls?
Spontaneously hypertensive rats exhibit significantly higher renal sympathetic activity compared to normotensive controls, suggesting a role for central nervous hyperreactivity in the development of primary hypertension.
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Renal sympathetic hyperactivity in SHR models is hypothesis-generating; leaves open translation to human primary hypertension.
Lundin et al. (1984) studied this question.
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