Characterization and quantification of lipid nanoparticle components and their impurities/degradants using an LC-HRAM MS platform

Key Points

• The aim is to characterize and quantify components of lipid nanoparticles, focusing on their impurities and degradants.
• Utilized LC-HRAM MS platform for analysis.
• Characterized lipid nanoparticle components and assessed impurities and degradants.
• Identified various components and impurities in lipid nanoparticles.
• Quantified the level of degradants present.