Key result
The GRACE 2.0 risk score demonstrated good discrimination for 1-year mortality (AUC=0.77) but inadequate discrimination for in-hospital mortality (AUC=0.62) in patients with NSTE-ACS.
Why the study?
Does the GRACE 2.0 risk score accurately predict in-hospital and 1-year mortality in patients with NSTE-ACS?
Population
396 consecutive non-ST-elevation acute coronary syndrome patients admitted to a tertiary hospital between…
Design
Cohort
Follow-up
1 year
Authors
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Supports GRACE 2.0 for 1-year mortality prediction in NSTE-ACS; leaves open its value for in-hospital risk stratification pending larger studies.
Cohort (n=396)
No
Does the GRACE 2.0 risk score accurately predict in-hospital and 1-year mortality in patients with NSTE-ACS?
Effect estimate: AUC 0.77 (1-year mortality)
The GRACE 2.0 risk score is a valid tool for predicting 1-year mortality in contemporary NSTE-ACS patients, but its utility for in-hospital mortality requires further validation in larger cohorts.
Akyüz et al. (2016) conducted a cohort in non-ST-elevation acute coronary syndrome (NSTE-ACS) (n=396). GRACE risk predictor (version 2.0) was evaluated on Discrimination and calibration performance for in-hospital and 1-year mortality (AUC 0.77 (1-year mortality)). The GRACE 2.0 risk score demonstrated good discrimination for 1-year mortality (AUC=0.77) but inadequate discrimination for in-hospital mortality (AUC=0.62) in patients with NSTE-ACS.
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