January 1, 2014Circulation JournalOpen Access

Diagnostic Accuracy of Global Registry of Acute Coronary Events (GRACE) Risk Score in ST-Elevation Myocardial Infarction for In-Hospital and 360-Day Mortality in Japanese Patients

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Why the study?

Does the GRACE risk score predict in-hospital and 360-day mortality in Japanese STEMI patients?

Population

412 consecutive Japanese patients with ST-elevation myocardial infarction who had undergone primary…

Design

Cohort

Follow-up

360 days

Authors

TFToshiharu FujiiTokai University TSToshihiko SuzukiTohoku University STSho ToriiTokai University

Discussion

Member takes

Implication

Supports GRACE use in Japanese STEMI; leaves open prospective validation before routine adoption.

Structured PICO

Does the GRACE risk score predict in-hospital and 360-day mortality in Japanese STEMI patients?

Population

412 consecutive Japanese patients with ST-elevation myocardial infarction (STEMI) who had undergone primary percutaneous coronary intervention, mean age 65.9 years, 79.9% male.

Intervention

GRACE 1.0 and GRACE 2.0 risk scores calculated on arrival in hospital

Outcome

In-hospital mortality (for GRACE 1.0) and 360-day mortality (for GRACE 2.0)hard clinical

The GRACE 1.0 and 2.0 risk scores demonstrate high diagnostic accuracy for predicting in-hospital and 360-day mortality in Japanese STEMI patients undergoing primary PCI.

Limitations

Retrospective study design
Small sample size which might be underpowered to draw a conclusion on diagnostic ability
Subject group selected with a focus on STEMI, whereas GRACE scores are established for all ACS
High mortality due to a high number of critical patients (cardiopulmonary arrest 7%, Killip IV 23%), which might differ from average Japanese STEMI patients

Cite This Study

Fujii et al. (2014) studied this question.

synapsesocial.com/papers/6a80c9e89ec2426b2722baf6 https://doi.org/10.1253/circj.cj-14-0808

Topics

Percutaneous coronary intervention

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Diagnostic Accuracy of Global Registry of Acute Coronary Events (GRACE) Risk Score in ST-Elevation Myocardial Infarction for In-Hospital and 360-Day Mortality in Japanese Patients

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Topics

Diagnostic Accuracy of Global Registry of Acute Coronary Events (GRACE) Risk Score in ST-Elevation Myocardial Infarction for In-Hospital and 360-Day Mortality in Japanese Patients

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

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