What question did this study set out to answer?

Determine whether aortic-valve sclerosis is associated with higher cardiovascular morbidity and mortality among older adults.

February 1, 2000Survey of Anesthesiology

Association of Aortic-Valve Sclerosis with Cardiovascular Mortality and Morbidity in the Elderly

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Determine whether aortic-valve sclerosis is associated with higher cardiovascular morbidity and mortality among older adults.
Prospective cohort analysis conducted within the Cardiovascular Health Study among community-dwelling adults aged 65 years and older.
Baseline echocardiographic assessments evaluated aortic-valve morphology to categorize valves as normal, sclerotic, or stenotic during longitudinal follow-up.
Aortic-valve sclerosis is associated with a significantly increased risk of cardiovascular death and incident myocardial infarction compared to normal valves.
Aortic-valve thickening reflects heightened vascular risk even in the absence of hemodynamically significant left ventricular outflow obstruction.

Implication

Cohort study reveals increased cardiovascular mortality and morbidity in elderly adults with aortic-valve sclerosis, suggesting valve thickening marks heightened systemic risk.

Abstract

OTTO, CATHERINE M.; LIND, BONNIE K.; KITZMAN, DALANE W.; GERSH, BERNARD J.; SISCOVICK, DAVID S. FOR THE CARDIOVASCULAR HEALTH STUDY Author Information

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Cite This Study

Otto et al. (2000) studied this question.

synapsesocial.com/papers/6a1ac65e7ff99bba06462777 https://doi.org/10.1097/00132586-200002000-00022

Topics

Cardiovascular prevention

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Implication

Cohort study reveals increased cardiovascular mortality and morbidity in elderly adults with aortic-valve sclerosis, suggesting valve thickening marks heightened systemic risk.

Abstract

OTTO, CATHERINE M.; LIND, BONNIE K.; KITZMAN, DALANE W.; GERSH, BERNARD J.; SISCOVICK, DAVID S. FOR THE CARDIOVASCULAR HEALTH STUDY Author Information

Association of Aortic-Valve Sclerosis with Cardiovascular Mortality and Morbidity in the Elderly

Key Points

Implication

Abstract

Discussion

Cite This Study

Topics

Association of Aortic-Valve Sclerosis with Cardiovascular Mortality and Morbidity in the Elderly

Key Points

Implication

Abstract

Discussion

Cite This Study

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