Key result
An automated algorithm using discrete wavelet transformation and nonlinear features of ECG signals achieved up to 98.34% accuracy, 95.49% sensitivity, and 99.14% specificity for 8-second segments.
A novel machine learning algorithm using DWT and nonlinear ECG features accurately differentiates shockable from nonshockable ventricular arrhythmias, potentially improving automated external defibrillator performance.
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May enhance AED arrhythmia detection; hypothesis-generating pending prospective clinical validation.
Shockable ventricular arrhythmias (VAs) such as ventricular tachycardia (VT) and ventricular fibrillation (VFib) are the life-threatening conditions requiring immediate attention. Cardiopulmonary resuscitation (CPR) and defibrillation are the significant immediate recommended treatments for these shockable arrhythmias to obtain the return of spontaneous circulation. However, accurate classification of these shockable VAs from nonshockable ones is the key step during defibrillation by automated external defibrillator (AED). Therefore, in this work, we have proposed a novel algorithm for an automated differentiation of shockable and nonshockable VAs from electrocardiogram (ECG) signal. The ECG signals are segmented into 5, 8 and 10[Formula: see text]s. These segmented ECGs are subjected to four levels of discrete wavelet transformation (DWT). Various nonlinear features such as approximate entropy ([Formula: see text], signal energy ([Formula: see text]), Fuzzy entropy ([Formula: see text]), Kolmogorov Sinai entropy ([Formula: see text], permutation entropy ([Formula: see text]), Renyi entropy ([Formula: see text]), sample entropy ([Formula: see text]), Shannon entropy ([Formula: see text]), Tsallis entropy ([Formula: see text]), wavelet entropy ([Formula: see text]), fractal dimension ([Formula: see text]), Kolmogorov complexity ([Formula: see text]), largest Lyapunov exponent ([Formula: see text]), recurrence quantification analysis (RQA) parameters ([Formula: see text]), Hurst exponent ([Formula: see text]), activity entropy ([Formula: see text]), Hjorth complexity ([Formula: see text]), Hjorth mobility ([Formula: see text]), modified multi scale entropy ([Formula: see text]) and higher order statistics (HOS) bispectrum ([Formula: see text]) are obtained from the DWT coefficients. Later, these features are subjected to sequential forward feature selection (SFS) method and selected features are then ranked using seven ranking methods namely, Bhattacharyya distance, entropy, Fuzzy maximum relevancy and minimum redundancy (mRMR), receiver operating characteristic (ROC), Student’s [Formula: see text]-test, Wilcoxon and ReliefF. These ranked features are supplied independently into the [Formula: see text]-Nearest Neighbor (kNN) classifier. Our proposed system achieved maximum accuracy, sensitivity and specificity of (i) 97.72%, 94.79% and 98.74% for 5[Formula: see text]s, (ii) 98.34%, 95.49% and 99.14% for 8[Formula: see text]s and (iii) 98.32%, 95.16% and 99.20% for 10[Formula: see text]s of ECG segments using only ten features. The integration of the proposed algorithm with ECG acquisition systems in the intensive care units (ICUs) can help the clinicians to decipher the shockable and nonshockable life-threatening arrhythmias accurately. Hence, doctors can use the CPR or AED immediately and increase the chance of survival during shockable life-threatening arrhythmia intervals.
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Oh et al. (2017) studied Ventricular arrhythmias. Automated differentiation algorithm using DWT and nonlinear features was evaluated on Classification accuracy, sensitivity, and specificity of shockable vs nonshockable arrhythmias. An automated algorithm using discrete wavelet transformation and nonlinear features of ECG signals achieved up to 98.34% accuracy, 95.49% sensitivity, and 99.14% specificity for 8-second segments.
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