Why the study?
Previous studies have shown controversial relationships between ACE I/D and ACTN3 R577x polymorphisms and athletic performance.
Do ACE I/D and ACTN3 R577x polymorphisms associate with athletic performance in Chinese youth male football players?
Population
73 elite, 69 sub-elite Chinese youth male football players, and 107 controls of Chinese Han origin
Comparison
Athletic performance across different ACE and ACTN3 gene profiles
Design
Genetic association case-control study
Key result
The ACTN3 XX genotype was associated with higher aerobic endurance in elite Chinese youth male football players, whereas ACE I/D and ACTN3 R577x polymorphisms were not associated with muscle power.
Authors
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ACTN3 XX may inform endurance selection in Chinese youth football; hypothesis-generating for ACE/ACTN3 performance links.
Case-Control (n=249)
Do ACE I/D and ACTN3 R577x polymorphisms associate with athletic performance in Chinese youth male football players?
ACE I/D and ACTN3 R577x polymorphisms are not associated with muscle power, but the ACTN3 XX genotype is associated with aerobic endurance in elite Chinese youth male football players.
Yang et al. (2023) conducted a case-control in Athletic performance (n=249). ACE I/D and ACTN3 R577x polymorphisms vs. Different genotypes (e.g., RR vs RX vs XX) was evaluated on Athletic performance indicators (muscle power, aerobic endurance, speed, explosive power). The ACTN3 XX genotype was associated with higher aerobic endurance in elite Chinese youth male football players, whereas ACE I/D and ACTN3 R577x polymorphisms were not associated with muscle power.