Why the study?
Are ACE I/D and ACTN3 R577X polymorphisms associated with elite athletic status in Taiwanese athletes?
Population
862 subjects in Taiwan, comprising 259 elite athletes training for the 2002 Asian Games and 603 general…
Comparison
Assessment of ACE I/D and ACTN3 R577X… vs General population controls
Design
Case-control
Key result
ACE I/D and ACTN3 R577X genotype distributions did not differ significantly between elite athletes and controls, though no athletes exhibited both the ACTN3 577XX and ACE DD genotypes.
Authors
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ACE/ACTN3 genotypes should not guide athlete selection; leaves open polygenic contributions to elite performance.
Case-Control (n=862)
Are ACE I/D and ACTN3 R577X polymorphisms associated with elite athletic status in Taiwanese athletes?
ACE I/D and ACTN3 R577X polymorphisms do not significantly differentiate elite athletes from the general population in Taiwan, suggesting athletic performance relies on multiple genetic traits.
Chiu et al. (2005) conducted a case-control in Elite athletes (n=862). ACE I/D and ACTN3 R577X polymorphism vs. General population controls was evaluated on Distribution of ACTN3 and ACE genotypes. ACE I/D and ACTN3 R577X genotype distributions did not differ significantly between elite athletes and controls, though no athletes exhibited both the ACTN3 577XX and ACE DD genotypes.