Relation of the Degree of Coronary-Artery Disease and of Myocardial Infarctions to Cardiac Hypertrophy and Chronic Congestive Heart Failure

HEART disease and heart failure in aging persons are usually assumed to be due to coronary arteriosclerosis (arteriosclerotic heart disease, ischemic heart disease) if other identifiable causes of heart disease can be excluded, notably hypertensive cardiovascular disease and chronic valvular disease. From time to time this assumption is challenged, and presbycardia (or "the senile heart") is believed by some to be produced by physiologic, biochemical or even morphologic alterations associated with old age, without relation to the degree of coronary disease.Another question is concerned with the causation of cardiac hypertrophy, which is one of the objective clinical findings most . . .