What does this research mean for the field?

Perimenopausal women with a history of severe polycystic ovary syndrome have a significantly higher risk of developing non-insulin dependent diabetes mellitus and coronary artery disease compared to the general population, despite having similar levels of traditional risk factors. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

April 1, 2000Human Reproduction

Increased risk of non-insulin dependent diabetes mellitus, arterial hypertension and coronary artery disease in perimenopausal women with a history of the polycystic ovary syndrome

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Why the study?

Does a history of polycystic ovary syndrome increase the risk of NIDDM, arterial hypertension, and coronary artery disease in perimenopausal women?

Population

780 perimenopausal women aged 45-59 years, comprising 28 women with a history of polycystic ovary syndrome…

Comparison

History of polycystic ovary syndrome with prior… vs Age-matched controls from a random female…

Design

Case-control

Authors

DCDavid CibulaCharles University

Discussion

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Implication

May warrant closer NIDDM and CAD surveillance in perimenopausal women with PCOS history; leaves open causal pathways and prospective validation.

Structured PICO

Does a history of polycystic ovary syndrome increase the risk of NIDDM, arterial hypertension, and coronary artery disease in perimenopausal women?

Population

780 perimenopausal women aged 45-59 years, comprising 28 women with a history of polycystic ovary syndrome (PCOS) who had undergone wedge ovarian resection, and 752 age-matched controls from a random female population sample.

Intervention

History of polycystic ovary syndrome (PCOS) with prior wedge ovarian resection

Comparator

Age-matched controls from a random female population sample

Outcome

Prevalence of non-insulin dependent diabetes mellitus (NIDDM), arterial hypertension, and coronary artery diseasehard clinical

Women with a history of severe PCOS are at a significantly higher risk for developing NIDDM and coronary artery disease by perimenopausal age, independent of traditional metabolic risk factors.

Cite This Study

David Cibula (2000) studied this question.

synapsesocial.com/papers/6a1aeec8a020f538e6859e20 https://doi.org/10.1093/humrep/15.4.785

Topics

Hypertension management Women and heart disease

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Implication

May warrant closer NIDDM and CAD surveillance in perimenopausal women with PCOS history; leaves open causal pathways and prospective validation.

Increased risk of non-insulin dependent diabetes mellitus, arterial hypertension and coronary artery disease in perimenopausal women with a history of the polycystic ovary syndrome

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Increased risk of non-insulin dependent diabetes mellitus, arterial hypertension and coronary artery disease in perimenopausal women with a history of the polycystic ovary syndrome

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider