Why the study?
Does saline infusion cause different urinary calcium excretion in hypertensive compared to normotensive subjects?
Population
15 subjects, comprising hypertensive (n=8) and normotensive (n=7) individuals
Comparison
Infusion of 2% saline at a rate of 11 mL/min for… vs Normotensive subjects receiving the same saline…
Design
Other
Follow-up
90 min
Authors
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May link volume homeostasis to calcium loss in hypertension; leaves open causal role and clinical relevance.
Does saline infusion cause different urinary calcium excretion in hypertensive compared to normotensive subjects?
Exaggerated natriuresis in hypertension is accompanied by hypercalcinuria, suggesting a link between sodium/volume homeostasis and calcium deficiency in hypertension.
Nakamura et al. (1991) studied this question.
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