Key result
Pre-operative ejection fraction > 50% was associated with significantly lower early post-operative mortality compared to ejection fraction < 50% (10% vs 25%, P=0.031) following CABG surgery.
Why the study?
Severe impairment of left ventricular function has been linked to poor outcomes after CABG, prompting evaluation of pre-operative LV function on early post-operative mortality and morbidity.
Does pre-operative left ventricular ejection fraction < 50% worsen early post-operative mortality and morbidity in patients undergoing CABG?
Cohort (n=40)
Does pre-operative left ventricular ejection fraction < 50% worsen early post-operative mortality and morbidity in patients undergoing CABG?
Answers are grounded in this paper and cite their sources.
Pre-operative left ventricular ejection fraction < 50% is associated with increased early post-operative mortality and longer ICU stays following CABG surgery.
Background : Studies have suggested that patients with severe impairment of left ventricular function had a poor outcome following CABG surgery. Objectives: Evaluation of the role of pre-operative left ventricular function on the early post-operative mortality and morbidity following CABG. Patients and methods: This study was carried out from August 2016 to January 2017 including 40 patients undergoing CABG surgery. Patients were divided into two equal groups each containing 20 patients. Group A contained 20 patients with pre-operative ejection fraction > 50%, while group B contained 20 patients with pre-operative ejection fraction < 50%. Results: Mortality was 2 patients in group A (10%) compared to 5 patients in group B (25%) (P value = 0.031). The mean ICU stay in group A was 3.29 ± 1.49 days compared to 4.22 ± 1.98 days in group B (P value = 0.028). Pre-operative renal dysfunction improved in 2 patients (10%) from group A, compared to 1 patient (5%) in group B (P value = 0.555). Conclusion: Left ventricular function as an independent factor is a good prognostic factor regarding the early postoperative outcome in coronary artery bypass grafting including mortality, operative times, ICU stay and hospital stay
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Ashkar et al. (2019) conducted a cohort in Coronary Artery Disease requiring CABG (n=40). Pre-operative ejection fraction > 50% vs. Pre-operative ejection fraction < 50% was evaluated on Early post-operative mortality (p=0.031). Pre-operative ejection fraction > 50% was associated with significantly lower early post-operative mortality compared to ejection fraction < 50% (10% vs 25%, P=0.031) following CABG surgery.
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