Key result
Preserved preoperative LVEF linked to ~58% lower odds of post-CABG arrhythmias.
Why the study?
The prognostic value of decreased preoperative LVEF for postoperative arrhythmias and mortality following CABG was uncertain.
Does lower preoperative LVEF predict increased risk of postoperative arrhythmias and mortality in patients undergoing on-pump CABG?
Observational (n=300)
Yes
Does lower preoperative LVEF predict increased risk of postoperative arrhythmias and mortality in patients undergoing on-pump CABG?
Odds Ratio: 0.418 (95% CI 0.316–0.553)
p-value: p=<0.001
Low preoperative LVEF is a powerful independent predictor of adverse early postoperative outcomes, including arrhythmias and in-hospital mortality, in patients undergoing on-pump CABG.
Background:: Following cardiac surgery, postoperative arrhythmias are frequent and substantial side effects. This study examines the wider prognostic practicality of decreased preoperative LVEF for postoperative consequences, including arrhythmias frequency, across a variety of cardiac surgical procedures, and mortality although it predicts poor outcomes in CABG. In patients having on pump CABG, this study seeks to determine if a lower preoperative LVEF is a risk factor of postoperative arrhythmia and mortality subsequent to them. Methodology: A cross sectional retrospective observational study was performed on 300 patients experiencing a preoperative left ventricular ejection fraction (LVEF) of ≤40% who underwent coronary artery bypass grafting (CABG). The main results were in hospital mortality and postoperative arrhythmias. Chi Square test was used to assess association between preoperative LVEF values and postoperative arrhythmias and mortality. Binary logistic regression analysis was performed to identify independent predictors, associated with postoperative arrhythmias and mortality. Statistical significance was defined as a p-value of less than 0.05. Results: The preoperative LVEF was notably decreased in patients who developed postoperative arrhythmias and those who experienced mortality. There was a significant association between reduced LVEF and these complications (p<0.001). LVEF was an independent predictor of arrhythmias and mortality in this study of 300 patients. Conclusion: Low preoperative LVEF is a strong independent predictor of postoperative arrhythmias and mortality in CABG patients. Those with severely reduced LVEF are at high risk for complications such as ventricular tachycardia, atrial fibrillation, and low cardiac output syndrome, underscoring the need for careful perioperative management despite the overall long term survival benefits of CABG.
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Mazhar et al. (2026) conducted an observational in Coronary artery disease requiring CABG (n=300). Reduced Preoperative Left Ventricular Ejection Fraction (LVEF) vs. Higher Preoperative LVEF was evaluated on Postoperative arrhythmias (OR 0.418, 95% CI 0.316-0.553, p=<0.001). Reduced preoperative left ventricular ejection fraction was significantly associated with a higher risk of postoperative arrhythmias (OR 0.418) and in-hospital mortality following coronary artery bypass grafting.
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