Key result
ACE inhibitor combinations with calcium channel blockers or diuretics improve blood pressure control and reduce cardiovascular and renal outcomes in hypertensive patients with type 2 diabetes.
Why the study?
What is the optimal ACE inhibitor combination therapy for reducing cardiovascular and renal outcomes in hypertensive patients with type 2 diabetes?
What is the optimal ACE inhibitor combination therapy for reducing cardiovascular and renal outcomes in hypertensive patients with type 2 diabetes?
This review highlights that combining an ACE inhibitor with a calcium channel blocker or diuretic provides synergistic benefits in blood pressure control and cardiovascular/renal protection for patients with diabetes and hypertension.
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Supports ACEi combinations for BP and outcomes in T2D hypertension; leaves open optimal regimen via prospective head-to-head trials.
Reboldi et al. (2009) conducted a review in Type 2 diabetes mellitus and hypertension. ACE inhibitor combinations was evaluated. ACE inhibitor combinations with calcium channel blockers or diuretics improve blood pressure control and reduce cardiovascular and renal outcomes in hypertensive patients with type 2 diabetes.
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