Key result
Myocardial T2 mapping in healthy subjects yielded an average normal T2 value of 52±6 ms (reference range 40-64 ms), with no significant differences between 1.5T and 3T magnetic fields.
Cross-Sectional (n=32)
No
Myocardial T2 mapping is feasible and establishes a normal global reference value of 52±6ms that is consistent across both 1.5T and 3T scanners.
Supports T2 reference implementation across scanners; leaves open validation in clinical populations.
Methods Between April and July 2014 we recruited 32 healthy subjects (no known cardiovascular risk factors, no previous history of heart disease), aged between 20 and 80yrs. All of them underwent a cardiovascular magnetic resonance (CMR at 1.5T, n=19; CMR at 3T, n= 13) protocol that included steady state free precession (SSFP) cines for measuring ventricular dimensions and function, TFisp 2D T2 mapping, dipyridamole stress myocardial perfusion study and late gadolinium enhancement study. T2 maps were obtained in three short axis orientations (basal, midventricular and apical). Regional myocardial T2 values were measured in a 16 segment model and global T2 values were also obtained per slice. A multifactorial ANOVA design was used for the statistical analysis.
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Maceira et al. (2015) conducted a cross-sectional in Healthy subjects (n=32). Myocardial T2 mapping vs. 1.5T vs 3T was evaluated on Normal myocardial T2 value (ms). Myocardial T2 mapping in healthy subjects yielded an average normal T2 value of 52±6 ms (reference range 40-64 ms), with no significant differences between 1.5T and 3T magnetic fields.
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