Key result
Native T1 and T2 mapping in cardiac MRI showed good to excellent global test-retest reproducibility (ICC 0.88 and 0.91, respectively), with significant regional differences.
Why the study?
Although native T1 and T2 mapping in cardiac MRI are invaluable for diagnosis and risk stratification, their global and regional reproducibility and the influence of demographic, physiological, and anatomical factors required investigation.
Does native T1 and T2 mapping in cardiac MRI have good test-retest reproducibility in healthy volunteers?
Cohort (n=50)
No
Does native T1 and T2 mapping in cardiac MRI have good test-retest reproducibility in healthy volunteers?
Effect estimate: ICC 0.88 for T1, ICC 0.91 for T2
Native T1 and T2 mapping in cardiac MRI demonstrates good to excellent global test-retest reproducibility, though significant regional variations exist, particularly in the inferior wall for T2 mapping.
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Global T1/T2 mapping reproducibility supports serial CMR research; leaves open regional standardization before clinical use.
Böttcher et al. (2021) conducted a cohort in Healthy volunteers (n=50). Native T1 and T2 mapping in cardiac MRI was evaluated on Global test-retest reproducibility of T1 and T2 values (ICC 0.88 for T1, ICC 0.91 for T2). Native T1 and T2 mapping in cardiac MRI showed good to excellent global test-retest reproducibility (ICC 0.88 and 0.91, respectively), with significant regional differences.
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