Key result
Catheter ablation for paroxysmal AF originating from the superior vena cava achieved a 73.3% freedom-from-AF rate at 5 years, with higher recurrence in patients with both SVC and PV triggers (P=0.012).
Why the study?
Does catheter ablation prevent AF recurrence in patients with drug-refractory, symptomatic paroxysmal AF originating from the superior vena cava?
Population
68 patients with drug-refractory, symptomatic paroxysmal atrial fibrillation originating from the superior…
Comparison
Catheter ablation of AF vs Patients with AF initiated from SVC only versus…
Design
Cohort
Follow-up
88 ± 50 months
Authors
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May support SVC isolation for select paroxysmal AF; hypothesis-generating and leaves open need for randomized confirmation.
Cohort (n=68)
Does catheter ablation prevent AF recurrence in patients with drug-refractory, symptomatic paroxysmal AF originating from the superior vena cava?
p-value: p=0.012
Catheter ablation provides long-term freedom from AF in 73% of patients with paroxysmal AF originating from the SVC at 5 years, with SVC isolation alone being an effective strategy for those without PV triggers.
Chang et al. (2012) conducted a cohort in Atrial fibrillation originating from the superior vena cava (n=68). Catheter ablation vs. SVC and PV triggers (Group 2) vs SVC triggers only (Group 1) was evaluated on AF recurrence (p=0.012). Catheter ablation for paroxysmal AF originating from the superior vena cava achieved a 73.3% freedom-from-AF rate at 5 years, with higher recurrence in patients with both SVC and PV triggers (P=0.012).
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