Why the study?
How does partial coronary flow disruption affect contractile function, oxidative energy production, and tissue high energy phosphate stores in isolated rabbit hearts?
How does partial coronary flow disruption affect contractile function, oxidative energy production, and tissue high energy phosphate stores in isolated rabbit hearts?
During partial coronary flow disruption, mechanical function is closely coupled to oxidative energy production, which preserves tissue high energy phosphate stores until severe ischemia.
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Supports metabolic preservation until severe impairment in animal ischemia; leaves open human translation and clinical relevance.
Robert C. Marshall (1988) studied this question.
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