What does this research mean for the field?

Cryoenergy application at growing myocardium does not cause coronary artery obstruction or intimal plaque formation early or late after the procedure. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

August 26, 2009Pacing and Clinical ElectrophysiologyOpen Access

Selective coronary angiography, intracoronary ultrasound, and histological examinations demonstrated no evidence of coronary artery obstruction or intimal proliferations up to 6 months after cryoenergy application.

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Why the study?

Does cryoenergy ablation cause coronary artery obstruction or intimal plaque formation in growing myocardium?

Population

10 piglets (age: 6 weeks, body weight: 14-18 kg)

Design

Preclinical

Follow-up

up to 6 months

Authors

TKThomas Kriebel HHHans‐Peter Hermann HSHeike Schneider

Discussion

Member takes

Overview

Supports further exploration of cryoenergy near coronaries in pediatric models; hypothesis-generating and should not yet change practice.

Structured PICO

Does cryoenergy ablation cause coronary artery obstruction or intimal plaque formation in growing myocardium?

Population

10 piglets (age: 6 weeks, body weight: 14-18 kg)

Intervention

Cryoenergy ablation (-75 degrees C for 4 minutes using a 7-F catheter with a 6-mm-tip electrode) at the atrial aspect of the tricuspid valve annulus and lateral/posterior atrial and ventricular aspect of the mitral valve annulus

Outcome

Coronary artery obstruction or intimal plaque formation assessed by coronary angiography, intracoronary ultrasound, and histological examinationssafety

Cryoablation appears safe for growing myocardium in a pediatric preclinical model, showing no evidence of subsequent coronary artery obstruction or intimal plaque formation.

Cite This Study

Kriebel et al. (2009) studied this question.

synapsesocial.com/papers/6a1b83fb0ac30a8853919b37 https://doi.org/10.1111/j.1540-8159.2009.02465.x

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August 26, 2009Pacing and Clinical ElectrophysiologyOpen Access

Selective coronary angiography, intracoronary ultrasound, and histological examinations demonstrated no evidence of coronary artery obstruction or intimal proliferations up to 6 months after cryoenergy application.

View Full Paper

Ask AI

Bookmark

Why the study?

Does cryoenergy ablation cause coronary artery obstruction or intimal plaque formation in growing myocardium?

Population

10 piglets (age: 6 weeks, body weight: 14-18 kg)

Design

Preclinical

Follow-up

up to 6 months

Authors

TKThomas Kriebel HHHans‐Peter Hermann HSHeike Schneider

Discussion

Member takes

Overview

Supports further exploration of cryoenergy near coronaries in pediatric models; hypothesis-generating and should not yet change practice.

Structured PICO

Does cryoenergy ablation cause coronary artery obstruction or intimal plaque formation in growing myocardium?

Population

10 piglets (age: 6 weeks, body weight: 14-18 kg)

Intervention

Outcome

Coronary artery obstruction or intimal plaque formation assessed by coronary angiography, intracoronary ultrasound, and histological examinationssafety

Cryoablation appears safe for growing myocardium in a pediatric preclinical model, showing no evidence of subsequent coronary artery obstruction or intimal plaque formation.

Cite This Study

Kriebel et al. (2009) studied this question.

synapsesocial.com/papers/6a1b83fb0ac30a8853919b37 https://doi.org/10.1111/j.1540-8159.2009.02465.x

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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