Why the study?
Does the full logistic EuroSCORE improve mortality prediction compared to the standard additive EuroSCORE in high-risk cardiac surgical patients?
Does the full logistic EuroSCORE improve mortality prediction compared to the standard additive EuroSCORE in high-risk cardiac surgical patients?
The logistic EuroSCORE provides better absolute mortality prediction than the additive model in high-risk cardiac surgical patients, despite similar discrimination.
Supports logistic EuroSCORE for better calibration in high-risk surgery; leaves open replacement of additive model in practice.
OBJECTIVES: To assess whether the use of the full logistic European System for Cardiac Operative Risk Evaluation (EuroSCORE) is superior to the standard additive EuroSCORE in predicting mortality in high-risk cardiac surgical patients. METHODS: Both the simple additive EuroSCORE and the full logistic EuroSCORE were applied to 14,799 cardiac surgical patients from across Europe, of whom there were 4293 high-risk patients (additive EuroSCORE of 6 or more). The systems were compared for absolute prediction and discrimination (area under the receiver operating characteristic (ROC) curve). RESULTS: Actual mortality was 4.72%. The logistic model was closer to this than the additive model (4.84% (4.72-4.94) versus 4.21 (4.21-4.26)). Most of this difference was due to high-risk patients where actual mortality was 11.18% and predicted was 7.83% (additive) and 11.23% (logistic). Discrimination was similar in both systems as measured by the area under the ROC curve (additive 0.783, logistic 0.785). CONCLUSIONS: The additive EuroSCORE model remains a simple "gold standard" for risk assessment in European cardiac surgery, usable at the bedside without complex calculations or information technology. The logistic model is a better risk predictor especially in high-risk patients and may be of interest to institutions engaged in the study and development of risk stratification.
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Michel et al. (2003) studied this question.
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