Why the study?
Patients with pulmonary embolism and contraindications to or failed thrombolysis face high mortality and may benefit from surgical embolectomy, but data remain limited.
What are the clinical outcomes and survival rates following surgical embolectomy in patients with acute pulmonary embolism?
What are the clinical outcomes and survival rates following surgical embolectomy in patients with acute pulmonary embolism?
Surgical pulmonary embolectomy provides a viable survival option for high-risk patients with acute pulmonary embolism and contraindications for or failed thrombolysis.
Substantial 30-day mortality after surgical embolectomy in high-risk PE warrants cautious patient selection; leaves open whether bleeding mitigation improves survival.
AIMS: Patients with pulmonary embolism (PE) and contraindications for or failed thrombolysis are at the highest risk for PE-related fatal events. These patients may benefit from surgical embolectomy, but data concerning this approach are still limited. METHODS: The method used here was retrospective data analysis of 103 patients who underwent surgical embolectomy from 2002 to 2020 at our department. RESULTS: Mean age was 58.4 (±15.1) years. Fifty-eight (56.3%) patients had undergone recent surgery; the surgery was tumor associated in 32 (31.1%) cases. Thirty (29.1%) patients had to be resuscitated due to PE, and 13 (12.6%) patients underwent thrombolysis prior to pulmonary embolectomy. Fifteen (14.5%) patients were placed on extra corporeal membrane oxygenation (ECMO) peri-operatively. Five patients (4.9%) died intra-operatively. Neurological symptoms occurred in four patients (3.9%). Thirty-day mortality was 23.3% ( n = 24). Re-thoracotomy due to bleeding was necessary in 12 (11.6%) patients. This parameter was also identified as an independent risk factor for mortality. CONCLUSION: Surgical pulmonary embolectomy resulted in survival of the majority of patients with PE and contraindications for or failed thrombolysis. Given the excessive mortality when left untreated, an operative approach should become a routine part of discussions concerning alternative treatment options for these patients.
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Panholzer et al. (2022) studied this question.
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