Why the study?
Does acute elevation of lipids via Intralipid and heparin infusion alter hemodynamics in human volunteers?
Population
32 human volunteers
Comparison
4-hour infusion of Intralipid and heparin vs 4-hour infusion of saline and heparin
Design
Other
Follow-up
4 hours
Authors
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Acute lipid infusion alters hemodynamics in volunteers; hypothesis-generating for lipid-driven cardiovascular risk mechanisms.
Does acute elevation of lipids via Intralipid and heparin infusion alter hemodynamics in human volunteers?
Acute elevation of plasma nonesterified fatty acids via Intralipid and heparin infusion increases blood pressure, heart rate, and systemic vascular resistance, suggesting a mechanism linking lipid abnormalities to cardiovascular risk.
Stojiljković et al. (2001) studied this question.
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