Why the study?
Does halothane reduce experimental myocardial ischemia in the non-failing canine heart?
Population
6 dogs with non-failing hearts under chloralose-urethane basal anesthesia, subjected to experimental…
Comparison
Halothane (0.75%) vs Control measurements before and after halothane…
Design
Preclinical
Authors
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Supports ischemia attenuation in canine models; hypothesis-generating for anesthetic effects on myocardial oxygen balance in humans.
Does halothane reduce experimental myocardial ischemia in the non-failing canine heart?
Halothane decreases the severity of experimentally-induced myocardial ischemia in the non-failing canine heart, likely by favorably altering the myocardial oxygen supply-demand relationship.
Bland et al. (1976) studied this question.
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