August 15, 2006Annals of Pharmacotherapy
Choosing the Appropriate Antithrombotic Agent for the Prevention and Treatment of VTE: A Case-Based Approach
Why the study?
What are the appropriate antithrombotic agents for the prevention and treatment of VTE across different patient populations?
Population
Patients requiring prevention or treatment of venous thromboembolism, including those undergoing orthopedic…
Design
Review
Authors
Discussion
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Member takes
Implication
Requires individualized VTE anticoagulant selection in practice; leaves open comparative trials across defined subgroups.
Structured PICO
What are the appropriate antithrombotic agents for the prevention and treatment of VTE across different patient populations?
P
Population
Patients requiring prevention or treatment of venous thromboembolism (VTE), including those undergoing orthopedic or general surgery, medically ill hospitalized patients, and patients with acute deep venous thrombosis or nonmassive pulmonary embolism.
I
Intervention
Pharmacologic antithrombotic agents including warfarin, unfractionated heparin (UFH), low-molecular-weight heparins (LMWH), and fondaparinux.
O
Outcome
Prevention and treatment of venous thromboembolism (VTE)
Individualized assessment of patient-specific factors is required to select the most appropriate antithrombotic agent for VTE prevention and treatment.
Cite This Study
Nutescu et al. (2006) studied this question.