What does this research mean for the field?

Q: What does this research mean for the field?

Excessive lipid accumulation within the myocardium (myocardial steatosis) is directly cardiotoxic and contributes to left ventricular remodeling and dilated cardiomyopathy in obese individuals. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.ESTABLISHES_NEW_DIRECTION.

April 4, 2006Annals of Internal Medicine

Adiposity of the Heart*, Revisited

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Population

Obese individuals and animal models of obesity

Design

Review

Authors

JMJonathan McGavockManitoba Health RVRonald G. VictorPennington Biomedical Research Center RURoger H. UngerDartmouth College

Discussion

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Implication

Myocardial steatosis merits prospective study in obesity cardiomyopathy; leaves open its biomarker or therapeutic utility.

Structured PICO

Population

Obese individuals and animal models of obesity

Outcome

Myocardial lipid accumulation and its role in left ventricular remodeling and dilated cardiomyopathy

Highlights myocardial steatosis as a novel mechanism for obesity-specific cardiomyopathy and a potential biomarker and therapeutic target.

Cite This Study

McGavock et al. (2006) studied this question.

synapsesocial.com/papers/6a1bca1fb33628da419cdd39 https://doi.org/10.7326/0003-4819-144-7-200604040-00011

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Adiposity of the Heart*, Revisited

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Adiposity of the Heart*, Revisited

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider