What does this research mean for the field?

The human cardiac muscle ryanodine receptor (hRyR-2) is a 4967-amino acid protein with a conserved C-terminal transmembrane domain that diverged early from a common ancestral gene to form a distinct branch of the RyR family. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.NEUTRAL.

September 1, 1996Biochemical JournalOpen Access

The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis

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Authors

RTRichard TunwellUniversity College London CWColin WickendenHammersmith Hospital BBBénédicte BertrandUniversidad Autónoma del Estado de Morelos

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Implication

Enables molecular studies of cardiac Ca2+ release defects; leaves open clinical translation pending functional validation.

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Cite This Study

Tunwell et al. (1996) studied this question.

synapsesocial.com/papers/6a1bcbbab33628da419ce00b https://doi.org/10.1042/bj3180477

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The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis

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Cite This Study

The human cardiac muscle ryanodine receptor-calcium release channel: identification, primary structure and topological analysis

Discussion

Member takes

Implication

Key Points

Cite This Study

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