Left ventricular markers of global dyssynchrony predict limited exercise capacity in heart failure, but not in patients with preserved ejection fraction
Why the study?
Do echocardiographic markers of global LV dyssynchrony predict limited exercise capacity in patients with heart failure?
Population
147 patients with heart failure (irrespective of ejection fraction), mean age 61 ± 11 years, 50.3% male.
Design
Cohort
Authors
Discussion
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Member takes
Implication
May support dyssynchrony assessment for exercise tolerance in HF; leaves open HFpEF-specific predictors and requires prospective validation.
Structured PICO
Do echocardiographic markers of global LV dyssynchrony predict limited exercise capacity in patients with heart failure?
P
Population
147 patients with heart failure (irrespective of ejection fraction), mean age 61 ± 11 years, 50.3% male.
I
Intervention
Echocardiographic assessment of global LV dyssynchrony (total isovolumic time [t-IVT] and Tei index)
O
Outcome
Functional capacity assessed by 6-minute walk test (6-MWT) distance (≤ 300 m vs >300 m)surrogate
Global LV dyssynchrony, assessed by total isovolumic time, predicts limited exercise capacity in heart failure overall, but not in patients with preserved ejection fraction.
Cite This Study
Bajraktari et al. (2012) studied this question.