Why the study?
Pulmonary vein isolation has suboptimal outcomes in persistent AF, prompting adjuvant ablation targeting substrate outside the pulmonary veins to improve procedural success.
Does adjuvant ablation over PVI improve success rates in patients with persistent atrial fibrillation?
Does adjuvant ablation over PVI improve success rates in patients with persistent atrial fibrillation?
This review summarizes current evidence on whether adjuvant ablation beyond pulmonary vein isolation improves outcomes in persistent atrial fibrillation.
Does not support routine adjuvant ablation beyond PVI in persistent AF; leaves open optimal lesion sets for future RCTs.
Pulmonary vein isolation (PVI) is a well-established treatment for atrial fibrillation (AF); however, studies report suboptimal outcomes in persistent AF. Adjuvant ablation targeting the substrate outside the pulmonary veins has been proposed to improve the success rates of the procedure. In this review, we summarize the current evidence regarding additional ablation over PVI in persistent AF. We describe the different approaches for adjuvant ablation, outcomes, and future perspectives.
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Terricabras et al. (2020) studied this question.
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