November 1, 1987Cleveland Clinic Journal of Medicine
Cardiopulmonary effects of chronic amiodarone therapy in the early postoperative course of cardiac surgery patients
Why the study?
Does chronic preoperative amiodarone therapy affect the early postoperative course in patients undergoing cardiac surgery?
Population
56 consecutive patients undergoing cardiac surgery
Comparison
Chronic amiodarone therapy prior to cardiac… vs Similar cardiac surgery without preoperative…
Design
Cohort
Follow-up
early postoperative course
Authors
Discussion
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Member takes
Implication
May increase postoperative respiratory failure risk after cardiac surgery; leaves open whether preoperative discontinuation reduces complications.
Structured PICO
Does chronic preoperative amiodarone therapy affect the early postoperative course in patients undergoing cardiac surgery?
P
Population
56 consecutive patients undergoing cardiac surgery (28 on preoperative amiodarone therapy, 28 given amiodarone later)
I
Intervention
Chronic amiodarone therapy prior to cardiac surgery (cumulative dose 373.6 ± 546.2 mg/kg over 60.5 ± 107.5 days)
C
Comparator
Similar cardiac surgery without preoperative amiodarone (patients were later given amiodarone)
O
Outcome
Early postoperative course (cardiopulmonary effects)
Cite This Study
Tuzcu et al. (1987) studied this question.