Why the study?
Does brief exercise- or pharmacologic-induced reversible myocardial ischemia increase high-sensitivity cardiac troponin T (hsTnT) levels in patients with suspected ischemic heart disease?
Does brief exercise- or pharmacologic-induced reversible myocardial ischemia increase high-sensitivity cardiac troponin T (hsTnT) levels in patients with suspected ischemic heart disease?
High-sensitivity cardiac troponin T levels do not increase following brief reversible myocardial ischemia induced by stress testing, suggesting elevations reflect irreversible myocyte death rather than reversible ischemia.
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hsTnT rises after stress testing should not be ascribed to reversible ischemia; supports necrosis-specific release but remains hypothesis-generating in observational data.
Kurz et al. (2008) studied this question.
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