Why the study?
Does brief exercise- or pharmacologic-induced reversible myocardial ischemia increase high-sensitivity cardiac troponin T (hsTnT) levels in patients with suspected ischemic heart disease?
Population
100 patients undergoing nuclear stress testing for suspected ischemic heart disease, after excluding…
Comparison
Nuclear stress testing with serial… vs Baseline hsTnT levels vs post-stress test levels…
Design
Cohort
Follow-up
24 hours
Authors
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hsTnT rises after stress testing should not be ascribed to reversible ischemia; supports necrosis-specific release but remains hypothesis-generating in observational data.
Does brief exercise- or pharmacologic-induced reversible myocardial ischemia increase high-sensitivity cardiac troponin T (hsTnT) levels in patients with suspected ischemic heart disease?
High-sensitivity cardiac troponin T levels do not increase following brief reversible myocardial ischemia induced by stress testing, suggesting elevations reflect irreversible myocyte death rather than reversible ischemia.
Kurz et al. (2008) studied this question.
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