Why the study?
Does the presence of vegetations on echocardiography predict the development of subsequent emboli in patients with left-sided native valve infective endocarditis?
Population
Patients with left-sided native valve infective endocarditis who had two-dimensional echocardiography within…
Comparison
Presence of vegetations visualized on… vs Absence of vegetations on two-dimensional…
Design
Cohort, Investigator-blinded
Authors
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Vegetations do not predict embolic events overall in left-sided native valve IE; leaves open microorganism-specific associations for prospective study.
Does the presence of vegetations on echocardiography predict the development of subsequent emboli in patients with left-sided native valve infective endocarditis?
Echocardiographic presence of vegetations does not significantly increase overall embolic risk in left-sided native valve endocarditis, but risk is microorganism-dependent and declines rapidly after starting antimicrobial therapy.
Steckelberg et al. (1991) studied this question.
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