Population
Patients with cardiovascular diseases, including essential hypertension, congestive heart failure, obesity…
Design
Review
Authors
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Supports sympathetic modulation as target in early CKD; leaves open efficacy of interventions like denervation pending RCTs.
Sympathetic overdrive is a key pathophysiological mechanism in hypertension, metabolic syndrome, and renal failure, highlighting it as a target for interventions like renal denervation.
Grassı et al. (2011) studied this question.
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