Why the study?
Does increasing coronary artery pressure alter myocardial reactive hyperemia following brief flow arrests in a canine model?
Population
20 closed-chest anesthetized dogs
Comparison
Increasing coronary pressure from 40 to 160 mmHg… vs Lower coronary pressures (e.g., 40 mmHg)
Design
Preclinical
Authors
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Coronary pressure modulates reactive hyperemia in canines; leaves open translation to human coronary physiology and ischemia assessment.
Does increasing coronary artery pressure alter myocardial reactive hyperemia following brief flow arrests in a canine model?
Coronary artery pressure has a major influence on the characteristics of myocardial reactive hyperemia after brief periods of arterial flow arrest, suggesting a passive flow response component.
Dole et al. (1981) studied this question.
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