What question did this study set out to answer?

To determine the elastic properties of coronary arteries in vivo and evaluate the impact of postmortem excision and cold storage on arterial elasticity.

November 1, 1979Circulation ResearchOpen Access

The elasticity of canine and human coronary arteries with reference to postmortem changes.

View Full Paper

Ask AI

Bookmark

Authors

BGBarry S. GowUNSW Sydney CHCathie HadfieldRoyal North Shore Hospital

Discussion

Member takes

Implication

Comparative experimental study demonstrates marked arterial stiffening after excision and cold storage in canine and human vessels, indicating postmortem data overestimate in vivo rigidity.

Key Points

To determine the elastic properties of coronary arteries in vivo and evaluate the impact of postmortem excision and cold storage on arterial elasticity.
Calculated dynamic and static incremental elastic moduli from simultaneous pressure and diameter traces in canine femoral and coronary arteries.
Developed a lightweight strain-gauge caliper to measure direct diameter recordings from the left circumflex coronary artery (LCCA) on beating canine hearts.
Assessed post-excision and overnight cold storage changes in canine muscular arteries and evaluated excised human coronary arteries (N=6, subjects aged 14–40 years).
Canine femoral arteries demonstrated diameter increases of 9.2% after excision and 11.6% after overnight cold storage, accompanied by static modulus increases of 77% and 173% and dynamic modulus increases of 46% and 99%.
Dynamic elastic modulus for the canine LCCA in vivo was 1.23 ± 0.12 × 10^5 N·m^-2, closely aligning with established femoral and carotid artery values.
Excised human coronary arteries (N=6) displayed static and dynamic moduli of 2.31 ± 0.49 × 10^5 N·m^-2 and 4.46 ± 1.21 × 10^5 N·m^-2, respectively, exhibiting higher stiffness than in vivo vessels.

Cite This Study

Gow et al. (1979) studied this question.

synapsesocial.com/papers/6a1be446c97d63156a5f1195 https://doi.org/10.1161/01.res.45.5.588

View Full Paper

Ask AI

Bookmark

Implication

Comparative experimental study demonstrates marked arterial stiffening after excision and cold storage in canine and human vessels, indicating postmortem data overestimate in vivo rigidity.

The elasticity of canine and human coronary arteries with reference to postmortem changes.

Discussion

Member takes

Implication

Key Points

Cite This Study

The elasticity of canine and human coronary arteries with reference to postmortem changes.

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider