What does this research mean for the field?

The dynamic compliance of epicardial coronary arteries decreases as initial distending pressure rises, and while systolic coronary flow volume matches vessel compliance under resting conditions, it significantly exceeds compliance during reactive hyperemia. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

December 1, 1970Circulation Research

Epicardial Coronary Artery Compliance in the Dog

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Population

21 coronary arteries from 17 dogs

Design

Preclinical

Authors

JDJohn E. DouglasUniversity of Montana JGJoseph C. GreenfieldAmerican Mosquito Control Association

Discussion

Member takes

Implication

Does not support clinical changes in coronary assessment; leaves open translation of pressure-dependent compliance to human hyperemia.

Structured PICO

Population

21 coronary arteries from 17 dogs

Intervention

In situ measurement of dynamic compliance (saline injection at 30 pulses/min) and static compliance (radiographically)

Outcome

Dynamic and static compliance of epicardial coronary arteriessurrogate

Epicardial coronary artery dynamic compliance decreases as distending pressure rises, and during reactive hyperemia, systolic flow markedly exceeds dynamic compliance.

Cite This Study

Douglas et al. (1970) studied this question.

synapsesocial.com/papers/6a1be446c97d63156a5f1198 https://doi.org/10.1161/01.res.27.6.921

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Epicardial Coronary Artery Compliance in the Dog

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Epicardial Coronary Artery Compliance in the Dog

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider