What does this research mean for the field?

A coronary input impedance model that accounts for blood inertia predicts the wall mechanics of coronary small arteries significantly better than a viscoelastic model, which overestimates the frequency dependence of compliance and phase lag. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

September 1, 1994AJP Heart and Circulatory Physiology

Compliance of isolated porcine coronary small arteries and coronary pressure-flow relations

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Structured PICO

Population

Six isolated porcine coronary small arteries (mean diameter 189 +/- 46 microns).

Intervention

Varying pressure (10-120 mmHg) and superimposing small pressure variations (0.1-10 Hz) at constant mean pressures; administration of acetylcholine to induce smooth muscle tone.

Comparator

Comparison of two models of coronary input impedance (viscoelastic vs. blood inertia effect).

Outcome

Normalized compliance (C0) and phase shift between pressure and cross-sectional area (CSA).surrogate

A model incorporating blood inertia better predicts the wall mechanics of isolated porcine coronary small arteries compared to a viscoelastic model.

Discussion

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Implication

Inertia-inclusive models merit testing in coronary mechanics research; leaves open translation beyond animal arteries.

Cite This Study

Giezeman et al. (1994) studied this question.

synapsesocial.com/papers/6a1a2ab39dd58c84b95b5eb2 https://doi.org/10.1152/ajpheart.1994.267.3.h1190

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Compliance of isolated porcine coronary small arteries and coronary pressure-flow relations

Structured PICO

Discussion

Implication

Cite This Study

Compliance of isolated porcine coronary small arteries and coronary pressure-flow relations

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider