Key result
The presence of passive myocardium restricts the compliance of the proximal LAD artery in situ compared to in vitro (4.85 vs 16.5 x 10-3 mm2/mmHg; P=0.009) and prevents collapse under compression.
Absolute Event Rate: 4.85% vs 16.5%
p-value: p=0.009
Myocardial tethering restricts the compliance of epicardial arteries under distension and prevents their collapse under compression.
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Myocardial tethering may influence epicardial mechanics in vivo; hypothesis-generating and leaves open human translation.
Hamza et al. (2003) studied Coronary artery compliance (n=6). In situ (with passive myocardium) vs. In vitro (without passive myocardium) was evaluated on Compliance of the proximal LAD artery under distension (x 10-3 mm2/mmHg) (p=0.009). The presence of passive myocardium restricts the compliance of the proximal LAD artery in situ compared to in vitro (4.85 vs 16.5 x 10-3 mm2/mmHg; P=0.009) and prevents collapse under compression.
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