Why the study?
Understanding of catheter-based pulsed field ablation of the ventricular myocardium is limited.
Does pulsed field ablation using a focal lattice-tip catheter effectively create lesions in normal and scarred porcine ventricular myocardium?
Does pulsed field ablation using a focal lattice-tip catheter effectively create lesions in normal and scarred porcine ventricular myocardium?
Pulsed field ablation using a focal lattice-tip catheter can effectively create ventricular lesions in both normal and scarred porcine myocardium, with lesion size increasing with more delivery repetitions.
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Informs PFA repetition dosing for larger ventricular lesions; leaves open translation to clinical scarred myocardium.
Kawamura et al. (2022) studied this question.
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