Why the study?
The prognostic impact of PCI for CTO in the acute setting during AMI remains controversial, particularly given the increased risk of complications associated with CTO-PCI.
Does percutaneous coronary intervention of chronic total occlusion improve prognosis in patients with acute myocardial infarction?
Does percutaneous coronary intervention of chronic total occlusion improve prognosis in patients with acute myocardial infarction?
This review discusses the controversial prognostic impact and increased complication risks of performing PCI on chronic total occlusions during acute myocardial infarction.
Coronary chronic total occlusion (CTO) has gained increasing clinical attention as the most advanced form of coronary artery disease. Prior studies already indicated a clear association of CTO with adverse clinical outcomes, especially in patients with acute myocardial infarction (AMI) and concomitant CTO of the non-infarct-related coronary artery (non-IRA). Nevertheless, the prognostic impact of percutaneous coronary intervention (PCI) of CTO in the acute setting during AMI is still controversial. Due to the complexity of the CTO lesion, CTO-PCI leads to an increased risk of complications compared to non-occlusive coronary lesions. Therefore, this review outlines the prognostic impact of CTO-PCI in patients with AMI. In addition, the prognostic impact of periprocedural myocardial infarction caused by CTO-PCI will be discussed.
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Kim et al. (2021) studied this question.
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