What does this research mean for the field?

Iron deficiency is highly prevalent in Southeast Asian patients with heart failure compared to community controls, and independently correlates with reduced functional capacity and poorer event-free survival. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

September 11, 2014European Journal of Heart Failure

Iron Deficiency in a Multi-Ethnic Asian Population with and Without Heart Failure: Prevalence, Clinical Correlates, Functional Significance and Prognosis

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Population

1,352 individuals including 751 heart failure patients and 601 community-based controls in a multi-ethnic…

Design

Cohort

Authors

TYTee Joo YeoPreventive Cardiology PYPoh Shuan Daniel YeoTan Tock Seng Hospital RWRaymond WongNational University of Singapore

Discussion

Member takes

Implication

May warrant iron assessment in Southeast Asian HF; extends Western data but leaves treatment effects open.

Structured PICO

Population

1,352 individuals including 751 heart failure patients (age 62.0 ± 12.2 years, 75.5% men) and 601 community-based controls (age 56.9 ± 10.4 years, 49.8% men) in a multi-ethnic Southeast Asian population (Chinese, Malay, Indian).

Comparator

Community-based controls without heart failure

Outcome

Prevalence of iron deficiency (defined as ferritin <100 µg/L or ferritin 100-300 µg/L and transferrin saturation <20%)surrogate

Iron deficiency is highly prevalent in Southeast Asian heart failure patients and is independently associated with reduced functional capacity and worse clinical outcomes.

Cite This Study

Yeo et al. (2014) studied this question.

synapsesocial.com/papers/6a1bf02f4ebd09f3dfa93ad2 https://doi.org/10.1002/ejhf.161

Topics

HFrEF treatment Heart failure

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