Why the study?
Manual titration of vasopressors to an arterial pressure target range in operating rooms and intensive care units may be improved by automated systems.
Do automated systems that titrate vasopressor infusions improve arterial pressure management compared to manual titration in high-risk surgical and critically ill patients?
Do automated systems that titrate vasopressor infusions improve arterial pressure management compared to manual titration in high-risk surgical and critically ill patients?
Automated blood pressure control systems represent a potential improvement over the current standard of manual vasopressor titration for managing sustained hypotension in the operating room and intensive care unit.
Should not yet change vasopressor titration practice; leaves open efficacy of automated systems pending randomized trials.
Arterial pressure management is a crucial task in the operating room and intensive care unit. In high-risk surgical and in critically ill patients, sustained hypotension is managed with continuous infusion of vasopressor agents, which most commonly have direct α agonist activity like phenylephrine or norepinephrine. The current standard of care to guide vasopressor infusion is manual titration to an arterial pressure target range. This approach may be improved by using automated systems that titrate vasopressor infusions to maintain a target pressure. In this article, we review the evidence behind blood pressure management in the operating room and intensive care unit and discuss current and potential future applications of automated blood pressure control.
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Rinehart et al. (2020) studied this question.
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