Population
Rabbit striated muscle alpha alpha-tropomyosin, rabbit fast-skeletal-muscle troponin-T, and corresponding…
Comparison
Phosphorylated forms of alpha alpha-TM and Tn-T vs Unphosphorylated forms of alpha alpha-TM and Tn-T
Design
Preclinical
Authors
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May modulate thin filament activation in animal models; leaves open relevance to human cardiac contractility.
Phosphorylation of alpha alpha-tropomyosin increases the activating propensity of thin filaments by modifying the functional properties of the T1 section of Tn-T.
David H. Heeley (1994) studied this question.
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