Population
Rabbit cardiac alpha alpha-tropomyosin
Comparison
Phosphorylated tropomyosin vs Nonphosphorylated tropomyosin
Design
Preclinical
Authors
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Preclinical reconstitution data require in vivo validation; leaves open tropomyosin phosphorylation effects on cardiac contractility.
Phosphorylation of rabbit cardiac alpha alpha-tropomyosin enhances head-to-tail interaction and increases ATPase activity in reconstituted systems, demonstrating its functional impact.
Heeley et al. (1989) studied this question.
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