Key result
SARS-CoV-2 infection in 7 patients with implantable cardioverter defibrillators was associated with 80 shocks, predominantly for ventricular tachycardia, alongside electrolyte abnormalities.
Why the study?
The relationship between SARS-CoV-2 infection and ICD shock remains unclear.
Observational (n=7)
No
SARS-CoV-2 infection may trigger ICD shocks, potentially mediated by electrolyte abnormalities, myocardial injury, and QT prolongation.
Answers are grounded in this paper and cite their sources.
Suggests monitoring ICD patients for shocks during SARS-CoV-2 infection; leaves open causality and generalizability.
Background: The relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and implantable cardioverter defibrillator (ICD) shock remains unclear. We analyzed the characteristics of patients receiving shocks after SARS-CoV-2 infection to explore the causes of these shocks and to provide information for subsequent treatment. Subjects and Methods: We retrospectively analyzed the data from seven patients hospitalized at First People’s Hospital of Yunnan Province between December 2022 and January 2023 after experiencing ICD shocks or ventricular arrhythmias following SARS-CoV-2 infection. We collected baseline information, data related to device parameters and events, and laboratory results to analyze the causes of electrical shocks. Results: All patients received ICD implantation at our hospital. The mean age of the patients was 67 ± 10 years. Four patients underwent implantation for primary prevention and three for secondary prevention. These patients received 80 ICD shocks after SARS-CoV-2 infection, 71 (89%), and 9 (11%) of which were the treatment for ventricular tachycardia and atrial fibrillation, respectively. There were 54 antitachycardia pacing treatments, of which 48 arrhythmic events were terminated through antitachycardia pacing, and 6 were not. Laboratory data revealed six patients had blood potassium levels below 4.0 mM. Five patients had blood calcium levels below 2.11 mmol/L. Four patients had elevated troponin concentrations (0.030–0.297 ng/mL). All patients had significantly elevated N-terminal pro-B-type natriuretic peptide levels (608.8–25,758 pg/mL). Six patients had a QT interval of >440 ms and a mean QT interval of 460 ± 46 ms. Conclusion: SARS-CoV-2 infection may be associated with ICD shocks. Clinicians should pay close attention to patients with ICDs after SARS-CoV-2 infection and actively eliminate arrhythmogenic triggers to minimize the likelihood of ICD shock.
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Sun et al. (2023) conducted an observational in ICD shocks after SARS-CoV-2 infection (n=7). SARS-CoV-2 infection was evaluated on Characteristics and causes of ICD shocks. SARS-CoV-2 infection in 7 patients with implantable cardioverter defibrillators was associated with 80 shocks, predominantly for ventricular tachycardia, alongside electrolyte abnormalities.
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