Key result
Pericardiocentesis and ABVD chemotherapy resolve cardiac tamponade and achieve complete response in Hodgkin lymphoma.
Why the study?
Cardiac implications of Hodgkin lymphoma remain poorly investigated, with few case reports of cardiac tamponade in these patients.
Case Report (n=1)
Cardiac tamponade is a rare but life-threatening initial manifestation of Hodgkin lymphoma that requires urgent pericardiocentesis and cytological/histological fluid analysis for diagnosis.
Prompts consideration of Hodgkin lymphoma in young adults with tamponade; leaves open whether routine fluid analysis improves outcomes.
Hodgkin lymphoma (HL) is an uncommon malignancy that is characterized by Hodgkin or Reed-Sternberg cells. Cardiac implications of HL remain one of the least investigated subjects. There are few case reports in the literature of cardiac tamponade in HL patients. We describe a case of a 21-year-old female patient who presented with cardiac tamponade as an initial presentation of HL. Any pericardial effusion significant for tamponade requires immediate drainage and fluid analysis for thorough investigation. Prompt identification and timely intervention are crucial in effectively addressing these complex situations. Therefore, clinicians should maintain heightened awareness in such cases.
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Kaiafa et al. (2024) conducted a case report in Hodgkin lymphoma presenting as cardiac tamponade (n=1). Pericardiocentesis and ABVD chemotherapy was evaluated. A 21-year-old female presenting with cardiac tamponade was diagnosed with Hodgkin lymphoma and achieved a complete response following pericardiocentesis and ABVD chemotherapy.
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