Why the study?
Does felodipine added to beta-blockers improve haemodynamics and exercise capacity in patients with stable angina pectoris?
Population
14 patients with stable angina pectoris already receiving beta-adrenoceptor blockers
Comparison
Felodipine added to beta-adrenoceptor blockade vs Placebo added to beta-adrenoceptor blockade
Design
RCT, crossover protocol, double-blind
Authors
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Felodipine added to beta-blockers improves exercise capacity and BP control in stable angina; extends evidence for dihydropyridine CCBs as adjunctive therapy.
Does felodipine added to beta-blockers improve haemodynamics and exercise capacity in patients with stable angina pectoris?
Adding felodipine to beta-blockers improves exercise duration and lowers blood pressure in patients with stable angina, though it does not significantly reduce angina episodes or GTN consumption.
Sheridan et al. (1987) studied this question.
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